Oligonucleotides, or oligos, are at the core of some of the most life-changing molecular biology tools used today. From qPCR to antisense gene therapy, oligos have changed what scientists can achieve through synthetic and molecular biology. While synthesis methods continue to advance, one significant challenge remains: oligo purification. Here, we explore the most common approaches to oligo purification, and explain how the right HPLC system can overcome any current and future challenges and help you achieve more accurate results.

Sample contamination is one of the biggest worries when it comes to sample integrity. It can occur at many stages of a laboratory’s operations, from sample collection, to transport, analysis, and storage. In this article, we explore the key drivers of contamination during pipetting, showing how the right tools and pipetting best practices help maximize sample integrity for consistent success.

Pipettes are an essential tool in the laboratory, but their importance goes beyond just the simple transfer of liquids. In fact, pipettes are paramount to sample integrity and, therefore, the accuracy, reliability, and reproducibility of your results. A big part of that is upkeep and keeping them free from contaminants – learn more in this article.

Using the right systems can improve sample integrity in your sample separation workflows, helping labs to have greater confidence in their results. Here we outline what to look for in your sample separation instruments to remove risks of common threats to sample integrity.

The quantitative polymerase chain reaction (qPCR) has transformed the world of molecular biology methodology by enabling fast, high-throughput detection and quantification of DNA and RNA in real time. PIPETMAX is specifically designed to maximize reproducibility and accuracy in qPCR workflows. Here, we explore three ways that PIPETMAX can help you run more effective and efficient experiments.

Switching from a manual to an automated process not only enables significantly more effective use of personnel time, but also removes operator error for reproducible results and increases the accuracy and precision of assays. In this article, we delve into the challenges that can arise during this transition and explain how Gilson's solutions and services can ease the process of transferring your manual methods to an automated system.

It is becoming increasingly clear that enhancing sustainability in the lab is not just about meeting regulatory requirements — it's a necessity to reduce environmental damage. Labs themselves can adopt sustainable processes by implementing more efficient and productive workflows. In this article, we delve deeper into the issue of chemical waste in labs and identify key areas where labs can significantly improve their sustainability.

Liquid chromatography (LC) is the standard method used for purifying products in the discovery stages, as it is cost-effective, relatively simple to perform, and reliable. However, obtaining high purity and yield using this approach often comes at the cost of throughput, as purification runs must be lengthened to achieve greater separation between components. This article explores how users can enhance fraction collection efficiency and streamline the purification process by using the latest advances.

How do you know you’re pipetting the volume you intend? Would you trust the results you’re getting if you didn’t know your pipettes were calibrated properly? Fortunately, there are standards that pipette manufacturers and calibration services follow so that you know you’re pipetting the correct volumes. Read more here.

When choosing a high performance liquid chromatography (HPLC) system, it's important to consider how your future needs may evolve from your current needs. In this article, you’ll learn about the advantages of modular HPLC systems when it comes to current experimental needs and how the ability to swap out HPLC components safeguards the future of your system and your research.