Lab scale purification, oftentimes referred to as research scale, is a way to discover new compounds. This type of purification allows you to purify enough of your lead compounds to identify, evaluate, and optimize against other targets.
We offer cost-effective and high throughput chromatography systems that support the purification of thousands of compounds per year. They are easy to use for fast method development and small-scale purification of up to 1-2 g for testing and identification. These systems are best for those executing purification research in new compound discovery or leads optimization.
Case Study: How Gilson is Helping Biotechs Scale-Up Peptide Purification for Drug Discovery
The Institute for Research and Innovation in Biomedicine (IRIB) focuses on developing innovative technologies for diagnosing, treating, and preventing diseases. Its research programs are centered around several themes, including cancer, infectious diseases, neurodegenerative diseases, and regenerative medicine. In this case study, we explore how the researchers at IRIB are using preparative HPLC in their peptide purification drug discovery applications.
With mid-size capacity and throughput, the VERITY 271 HPLC systems provide many customized configurations for semi-preparative and preparative purifications to match user’s needs. All system configurations accommodate novel injection and fraction collection capabilities within a single platform, with multiple detection options. Using the powerful TRILUTION® LC software, the system is intuitive and easy to control.
The VERITY® CPC Lab System combines a PLC Purification System with a centrifugal partition chromatography (CPC) system for high-level target compound purification at a lab scale. This automated, cost-effective, liquid-liquid purification technique utilizes reusable, silica-free chromatographic columns to streamline your workflow and allow you to quickly isolate specific molecules with high yields and purity.
The VERITY® CPC Lab MS System allows you to perform mass-directed purification of target compounds by centrifugal partition chromatography (CPC). This automated, cost-effective, liquid-liquid purification technique utilizes reusable, silica-free chromatographic columns and the VERITY® 1920 Mass Spectrometer to streamline your workflow and allow you to quickly isolate added value molecules with high yields and purity.
